You should go with a high cushioning shoe (even though you are not THAT heavy), since impact forces to your knee are 2-3 your weight, + your shoes may get used faster. The choice you will make depends upon other factor, mostly pronation (http://www.runningwarehouse.com/LearningCenter/PronationFAQ.html), price $$ and type of running (you say you run 5-10 miles a week : do you compete or you just train yourself?). Knowing this, you might consider : Nimbus or Cumulus by Asics, or Glycerine or Defyance by Brooks. I don't know that much about Adrenaline but it might be a good choice. The best you can do is go to your local shoe store and ask them about this. Good luck,

-Khad

I can definitely recommend the Adrenaline. I went through a few pairs of those before I stepped up to the Brooks Radius, which I would also highly recommend.

I think the most important thing though is to go to a good running store. One where they can at least look at you walk or run. And one where they look at the wear patterns on your current shoes. Follow their recommendations.

Whoa! Slow down here! Just because the shoe wears on the outside of the hell does not mean you will need a motion control shoe. I sold shoes in a specialty running store for a very long time and the number of motion control shoes I sold was extremely low. Most people that wear them don't need that much support.
If you don't know for sure if you pronate or under-pronate (supinate), then you need to start there. Just keep trying shoes on. You'll find the right ones. Just last week I went in and tried on 13 pairs! :D

When you do find the perfect shoes, you should buy multiple pairs so you don't wear them out as fast. I too am on the heavier side. I tend to wear my shoes out before the 300 miles. My friend, who's a marathon runner, told me to have a different pair for each day that I run, about 3-4 days/week. I was spending $100+ for new running shoes every couple months. So, I was lucky enough to get a pass to the Nike employee store, and found my perfect shoe.....bought 3 pairs (Nike Vomeros 2). I have flat and wide feet and when I first tried these shoes out, they were so comfortable. I agree with everyone else that you should have a pro analyze your gait.

Perfectly said.

I am 6'2" and 205 and I can tell you what I wear, but a good running shoe store will tell you what is good for your running style.

Thanks again for all you input.

I got myself to a running store and was assessed. I found out I am a neutral runner.

The shoes that I loved the most were the Nike Vomero +3 , and the Brooks Glycerin 6 more superior than the NB 991 that were more for flat footed runners.